The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)

The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)

The ability to respond to stress is at the core of an organism's survival. The hormones epinephrine and norepinephrine play a central role in stress responses in mammals, which require the synchronized interaction of the whole neuroendocrine system. Mammalian adrenergic receptors are G-coupled protein receptors (GPCRs); bacteria, however, sense these hormones through histidine sensor kinases (H...

Enterohemorrhagic E. coli (EHEC) pathogenesis

Enterohemorrhagic Escherichia coli (EHEC) serotype O157:H7 is a human pathogen responsible for outbreaks of bloody diarrhea and hemolytic uremic syndrome (HUS) worldwide. Conventional antimicrobials trigger an SOS response in EHEC that promotes the release of the potent Shiga toxin that is responsible for much of the morbidity and mortality associated with EHEC infection. Cattle are a natural r...

Enterohemorrhagic Escherichia coli (EHEC).

Enterohaemorrhagic Escherichia coli has since the last 2 decades been known to cause severe and bloody diarrhoea as well as haemorrhagic colitis (HC) and haemorrhagic uraemic syndrome (HUS) especially among children. The importance of screening for EHEC among children and older patients with severe symptoms is apparent. Production of the verocytotoxins VT1 and VT2 are the main features of EHEC,...

Enterohemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli

Enterohemorrhagic Escherichia coli (EHEC) Findings from Humans in Finland

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